Scientists & Research
Recent Research Publications
Belfiore, C. J., Yang, R. S. H., Chubb, L. S., Lohitnavy, M., Lohitnavy, O. S., and Andersen, M. E. (2007). Hepatic sequestration of chlordecone and hexafluoroacetone evaluated by pharmacokinetic modeling. Toxicology 234, 59-72.
Cruzan, G., Borghoff, S. J., de Peyster, A., Hard, G. C., McClain, M., McGregor, D. B., and Thomas, M.G. (2007). Methyl tertiary-butyl ether mode of action for cancer endpoints in rodents. Regul. Toxicol. Pharmacol. 47, 156-165.
Li, L., Andersen, M. E., Heber, S., and Zhang, Q. (2007). Non-monotonic dose-response relationship in steroid hormone receptor-mediated gene expression J. Mol. Endocrinol. 38, 569-585.
Liu, H. Y., Collins, Q. F., Xiong, Y., Moukdar, F., Lupo Jr., E. G., Liu, Z., and Cao, W. (2007). Prolonged treatment of primary hepatocytes with oleate induces insulin resistance through p38 mitogen-activated protein kinase. J. Biol. Chem. 282(19):14205-14212.
Wong, B. A. (2007). Inhalation exposure systems: Design, methods and operation. Toxicol. Pathol. 35(1), 3-14.
Sochaski, M. A., McManus, B. M., Struve, M. F., Wallace, D. G., and Dorman, D. C. (2007). Inhibition and recovery of maternal and foetal cholinesterase enzymes following fenitrothion administration in CD rats. Xenobiotica 37, 19-29.
Thomas, R. S., O'Connell, T. M., Pluta, L., Wolfinger, R. D., Yang, L., and Page, T. P. (2007). A comparison of transcriptomic and metabonomic technologies for identifying biomarkers predictive of two-year rodent cancer bioassays. Toxicol. Sci. 96, 40-46.
Xiong, Y., Collins, Q. F., An, J., Lupo, E. G. Jr., Liu, H.-Y., Liu, D., Robidoux, J., Liu, Z., and Cao, W. (2007). p38 mitogen-activated protein kinase plays an inhibitory role in hepatic lipogenesis. J. Biol. Chem. 282, 4975-4982.
Zager, M. G., Schlosser, P. M., and Tran, H. T. (2007). A delayed nonlinear PBPK model for genistein dosimetry in rats. Bull. Math. Biol. 69, 93-117.
Zhang, Q. and Andersen, M. E. (2007). Dose response relationship in anti-stress gene regulatory networks. PLoS Comput. Biol. Mar 2; 3(3):e24.
Collins, Q. F., Xiong, Y., Lupo, E. G. Jr., Liu, H.-Y., and Cao, W. (2006). p38 mitogen-activated protein kinase mediates free fatty acid-induced gluconeogenesis in hepatocytes. J. Biol. Chem. 281, 24336-24344.
Ingram, J. I., Antao-Menezes, A., Mangum, J. B., Lyght, O., Lee, P. J., Elias, J. A., and Bonner, J. C. (2006). Opposing actions of Stat1 and Stat6 on IL-13-induced up-regulation of early growth response-1 and platelet-derived growth factor ligands in pulmonary fibroblasts. J. Immunol. 177, 4141-4148.
Ingram, J. L. and Bonner, J. C. (2006). EGF and PDGF receptor tyrosine kinases as therapeutic targets for chronic lung diseases. Curr. Mol. Med. 6, 409-421.
Lahousse, S. A., Wallace, D. G., Liu, D., Gaido, K. W., and Johnson, K. J. (2006). Testicular gene expression profiling following prepubertal rat mono-(2-ethylhexyl) phthalate exposure suggests a common initial genetic response at fetal and prepubertal ages. Toxicol. Sci. 93, 369-381.
Pasquale-Styles, M. A., Sochaski, M. A., Dorman, D. C., Krell, W. S., Shah, A. K., and Schmidt, C. J. (2006). Fatal bromethalin poisoning. J. Forensic Sci. 51, 1154-1157.
Schroeter, J. D., Kimbell, J. S., and Asgharian, B. (2006). Analysis of particle deposition in the turbinate and olfactory regions using a human nasal computational fluid dynamics model. J. Aerosol Med. 19, 301-313.
Schroeter, J. D., Kimbell, J. S., Andersen, M. E., and Dorman, D. C. (2006). Use of a pharmacokinetic-driven computational fluid dynamics model to predict nasal extraction of hydrogen sulfide in rats and humans. Toxicol. Sci. 94, 359-367.
Swift, D., Asgharian, B., and Kimbell, J. S. (2006). Use of mathematical aerosol deposition models in predicting the distribution of inhaled therapeutic aerosols. Chapter 3. In: Inhalation Aerosols: Physical and Biological Basis for Therapy, Second Edition (Hickey, A. J., editor), pp. 51-84. Marcel Dekker, New York.
Yokley, K., Tran, H. T., Pekari, K., Rappaport, S., Riihimaki, V., Rothman, N., Waidyanatha, S., and Schlosser, P. M. (*2006). Physiologically-based pharmacokinetic modeling of benzene in humans: A Bayesian approach. Risk Anal. 26, 925-943.
Zhang, Q., Andersen, M. E., and Conolly, R. B. (2006). Binary gene induction and protein expression in individual cells. Theor. Biol. Med. Model. Apr 5; 3:18.