Education and Outreach

Dianxin Liu, M.D., Ph.D.

Division of Biological Sciences

Dianxin Liu, M.D., Ph.D.

Education

M.D., preventive medicine, Shandong Medical University, Shandong province, China, 1988.
Ph.D., molecular genetics, Institute of Biotechnology, Chinese Academy of Military Medical Sciences, Beijing, China, 1998.
M.S., Nutrition, Institute of Health and Environmental Medicine, Chinese Academy of Military Medical Sciences, Beijing, China, 1992.
Postdoctoral training, Laboratory of Signal Transduction and Laboratory of Reproductive Developmental Toxicology, National Institute of Environmental Health Sciences, Research Triangle Park, NC, 2001-2006.
Postdoctoral training, Division of Biological Sciences, CIIT Centers for Health Research, Research Triangle Park, North Carolina, 2006-present.

Research

The previous research in the Collins laboratory shows that p38 alpha MAPK plays an important role for regulation of UCP1 gene expression mediated by either beta3 adrenergic receptor or cold exposure. Under the supervision of Dr. Sheila Collins, my focus is the conditional disruption of p38 alpha in adipose tissue to understand the essential role of p38 MAPK in the signal cascade of adipose tissues.

Selected Publications

Liu, D., Zhang, Z., and Teng, C.T. (2005). Estrogen-related receptor-gamma and peroxisome proliferator-activated receptor-gamma coactivator-1alpha regulate estrogen-related receptor-alpha gene expression via a conserved multi-hormone response element. J. of Mol. Endocrinol. 34, 473-487.

Liu, D., Zhang, Z., Gladwell, W., and Teng, C.T. (2003) Estrogen stimulates estrogen-related receptor alpha gene expression through conserved hormone response elements. Endocrinology 144, 4894-4904.

Liu, D., Xin, W., Zhang, Z., and Teng, C.T. (2003). An intronic alternative promoter of the human lactoferrin gene is activated by Ets. Biochem. Biophys. Res. Commun. 301, 472-479.

Liu, D., Zhang, F., Ma, Q., and Gu, J. (1999). Effect of human prothymosin alpha on the immune function in aging and zinc deficiency. Acta Nutri. Sin. 21, 153-158.