Education and Outreach

Jerry Campbell, Jr., Ph.D.

Division of Computational Biology

Education

Ph.D., Toxicology, University of Georgia, Athens, Georgia, 2004.
M.S., Environmental Health Science, University of Georgia, Athens, Georgia, 1997.
B.S., Environmental Health Science, University of Georgia, Athens, Georgia, 1993.

Research

Under the guidance of Mr. Harvey Clewell, Dr. Melvin Andersen, and Dr. Cecilia Tan, my research will focus on the development of a "State of the Science" risk assessment for dibutylphthalate (DBP). Concern has arisen over recent research implicating DBP (as well as other phthalate diesters) in the disruption of testosterone production in the male fetus resulting in male reproductive malformations. The primary basis of this research will be the development of a human physiologically-based pharmacokinetic (PBPK) model to describe the prenatal and neonatal exposure to DBP. The DBP PBPK model will incorporate human metabolic parameters measured in vitro. Once completed, the PBPK model for DBP will be employed to investigate human exposure to DBP through interpretation of biomonitoring data.

Selected Publications

Fisher, J. W., Campbell, J., Muralidhara, S., Bruckner, J. V., Ferguson, D., Mumtaz, M., Harmon, B., Hedge, J. M., Crofton, K. M., Kim, H., and Almekinder, T. L. (2006). Effect of PCB 126 on hepatic metabolism of thyroxine and perturbations in the hypothalamic-pituitary-thyroid axis in the rat. Toxicol. Sci. 90, 87-95.

Dietzel, K. D., Campbell, J. L., Bartlett, M. G., Witten, M. L., and Fisher, J. W. (2005). Validation of a gas chromatography/mass spectrometry method for the quantification of aerosolized Jet Propellant 8. J. Chromatogr. A 1093, 11-20.

Smith, A. Q., Campbell, J. L., Keys, D. A., and Fisher, J. W. (2005). Rat tissue and blood partition coefficients for n-alkanes (C8 to C12). Int. J. Toxicol. 24, 35-41.

Campbell, J. L. Jr., Smith, M. A., Fisher, J. W., and Warren, D. A. (2004). Dose-response for retinoic acid-induced forelimb malformations and cleft palate: a comparison of computerized image analysis and visual inspection. Birth Defects Res. B Dev. Reprod. Toxicol. 71, 289-295.

Lumpkin, M. H., Bruckner, J. V., Campbell, J. L., Dallas, C. E., White, C. A., and Fisher, J. W. (2003). Plasma binding of trichloroacetic acid in mice, rats, and humans under cancer bioassay and environmental exposure conditions. Drug Metab. Dispos. 31, 1203-1207.

Campbell, J. L., Smith, M. A., Eiteman, M. A., Williams, P. L., and Boeniger, M. F. (2000). Comparison of solvents for removing pesticides from skin using an in vitro porcine model. AIHAJ 61, 82-88.

Santerre, C. R., Campbell, J. L., Farina, P. C., and Muse, L. A. (1995). Assessing tritium contamination on three surfaces. Appl. Radiat. Isot. 46, 261-267.

Campbell, J. L., Santerre, C. R., Farina, P. C., and Muse, L. A. (1993). Wipe testing for surface contamination by tritiated compounds. Health Phys. 64, 540-544.